摘要
目的探讨布-加综合征围手术期的危险因素。方法回顾性分析1995—2004年收治的布-加综合征确诊者中514例的临床资料。全组患者均行手术治疗。结果单因素分析发现年龄、合并症、吸烟、饮酒、腹水、黄疸、电解质紊乱、营养状况、术后低血压、术中出血、白蛋白、手术时间、手术时机、病理类型、血糖、出血史和凝血酶原时间(χ2=-5.089～234.858,P=0～0.028)等可能是布-加综合征围手术期的危险因素。多变量Logistic回归分析结果提示饮酒、病理类型、手术时间、术中失血、营养状况、术后低血压、黄疸、电解质紊乱、血糖和严重并发症(χ2=-0.912～2.147,P=0～0.07)等10指标为布-加综合征围手术期的独立危险因素。结论布-加综合征围手术期的高危因素能很好的反映布-加综合征患者围手术期的危险性,为手术时机的选择和指导预后有一定的临床参考价值。
Objective To evaluate the peri-operative risk factors in patients with Budd-Chiari syndrome （B-CS）. Methods Five hundred and forteen cases of B-CS with complete clinical data were analyzed retrospectively. All the patients underwent surgical procedures. Results The univariate analysis revealed that age, concomitant disease, smoking, drinking, ascites, jaundice, electrolyte disorder, nutrition, postoperative hypotension, operative blood loss, albumin level, operation time, operation timing, pathologic classification, level of blood sugar, history of hemorrhage and prothrombin time （ X^2 = - 5. 089 -234. 858 , P = 0- 0. 028 ） were possible perioperative risk factors of Budd-Chiari syndrome. The multivariate logistic regression analysis demonstrated that alcohol drinking, pathologic classification, operation time, operative blood loss, nutritional status, postoperative hypotension, jaundice, electrolyte disorder, level of blood sugar and severe complications （ X^2 = - 0. 912 - 2. 147 , P = 0 - 0. 07 ） were independent peri-operative risk factors of Budd-Chiari syndrome. Conclusions Peri-operative high risk factors of Budd-Chiari syndrome can reflect the risks of Budd-Chiari syndrome, and can be very valuable as clinical reference for selection of operation timing and evalution of prognosis.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2009年第6期561-563,共3页
China Journal of General Surgery
关键词
布-加综合征
围手术期
危险因素
Budd-Chiari Syndrome
Peroperative Period
Risk Factors
