咪达唑仑复合丙泊酚在ICU机械通气患者中的应用被引量：5

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摘要 ①目的探讨咪达唑仑复合丙泊酚用于ICU机械通气患者的镇静效果。②方法诱导量：咪达唑仑组0.1-0.2mg/kg,丙泊酚组1-2mg/kg,咪达唑仑联合丙泊酚联合用药组0.1mg/kg＋丙泊酚1mg/kg;维持量：咪达唑仑组0.04-0.16 mg/（kg.h）,丙泊酚组0.5-4mg/（kg.h）,咪达唑仑＋丙泊酚组咪达唑仑0.08mg/（kg.h）＋丙泊酚1-2mg/（kg.h）。③结果咪达唑仑＋丙泊酚组在药物起效时间、达到满意深度时间、恢复时间及清醒后再入睡率等与咪达唑仑组比较,差异有统计学意义（P〈0.05）。④结论咪达唑仑与丙泊酚联合应用,镇静效果满意,可以减少不良反应,降低费用,是ICU机械通气患者镇静治疗较为理想的治疗方案。

作者王旭东

机构地区徐州医学院第二附属医院ICU

出处《华北煤炭医学院学报》 2009年第3期321-322,共2页 Journal of North China Coal Medical College

关键词镇静机械通气咪达唑仑丙泊酚

分类号 R971.3 [医药卫生—药品]

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