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大疱性类天疱疮抗原1和2在大疱性类天疱疮并发神经系统损害中的作用 被引量:2

The role of bullous pemphigoid antigen 1 and 2 in bullous pemphigoid accompanied by neurological diseases
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摘要 大疱性类天疱疮可见于多种神经系统疾病患者,二者并发的机制尚不清楚。动物研究证实鼠大疱性类天疱疮抗原(BPAG)1至少存在3种亚型:皮肤亚型、神经亚型和肌肉亚型。BPAG2除在皮肤有表达外,在人脑神经元也有广泛表达。有可能神经系统病变导致BPAG1和BPAG2神经亚型暴露于免疫系统,产生拮抗神经亚型的抗体,与皮肤亚型发生免疫反应及交叉反应,导致大疱性类天疱疮发生。
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2009年第7期477-479,共3页 Journal of Clinical Dermatology
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参考文献14

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二级参考文献12

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