摘要
目的评价美罗培南治疗老年人医院获得性肺部感染时的疗效和安全性。方法回顾性分析73例使用美罗培南治疗的老年严重肺部感染患者共96例次,记录临床症状、细菌清除情况、不良反应等。结果美罗培南治疗老年人医院内获得性肺部感染的有效率为76.04%(73/96),细菌清除率为71.70%(76/106),对耐亚胺培南的铜绿假单胞菌有一定疗效。不良反应发生率3.77%。在11例次慢性肾功能不全患者的应用中有很好的安全性。结论美罗培南治疗严重的老年人医院内获得性肺部感染疗效明显,安全性好。
Objective To investigate the clinical efficacy and safety of meropenem in older nosocomial infection patients Methods Seventy-three older nosoeomial infection patients and ninety-six times using meropenem were observed to analyses the clinical efficacy and the bacterial eradication and the clinical adverse effect,et al. Results Clinical total effective rates were 76.04%（73/96）,the bacterial eradication rates were 71.70%（76/106）,the clinical adverse effect were 3.77%. There was a great safety in the use of 11 chronic renal failure. Conclusions There were well clinical efficacy and safety in using meropenem in older nosocomial infection patients.
出处
《中国老年保健医学》
2009年第2期41-42,共2页
Chinese Journal of Geriatric Care
关键词
美罗培南
老年人
医院感染
meropenem,older patients,nosoeomial infection
