摘要
目的观察神经生长因子(NGF)在颅脑损伤救治中的临床疗效。方法脑外伤患者60例,分为两组,对照组30例,予以常规治疗;NGF组30例,在对照组的基础上应用NGF(≥9000AU),静脉滴注,间隔12h给药,连续给药28d。在治疗结束后及3个月后分别进行格拉斯哥预后(GOS)评分,并进行统计学分析。结果NGF组的GOS评分方面明显优于对照组(P<0.05),静脉给药未见不良反应。结论NGF可以促进脑功能的恢复,提高颅脑损伤救治的临床疗效;静脉给药是一种安全的给药方式。
Objective To observe the clinical effect of the nerve growth factor （NGF） in the treatment of traumatic brain injury. Methods Sixty cases of traumatic brain injury were divided into two groups. In control group, 30 cases underwent conventional treatment, and in the treatment group, 30 cases were treated with NGF （≥9 000 AU）, ivgtt, ql2h, 28 days for a course of treatment. CA）S score was applied at the end and after 3 months of treatment, and was analyzed statistically. Results In the treatment group, the GOS score was significantly higher than that in control group （P 〈0. 05）. There were no obvious adverse reactions during the intravenous administration. Conclusion NGF can promote the recovery of brain function, and improve the clinical effect of traumatic brain injury. Intravenous administration is a safe and effective way.
出处
《华中医学杂志》
2009年第3期134-136,共3页
Central China Medical Journal
关键词
神经生长因子
颅脑损伤
预后
Nerve growth factor
Brain injury
Prognosis
