摘要
目的了解老年慢性阻塞性肺疾病(COPD)患者痰菌状况及耐药情况。方法对238例老年科住院的COPD患者痰菌分离培养,药敏试验采用M IC法。结果革兰阴性菌487株(500株)占97.4%,其中不动杆菌属、铜绿假单胞菌、肺炎克雷伯菌为主要病种。药敏结果表明细菌耐药性为增强,但亚胺培南、环丙沙星、哌拉西林/他唑巴坦、阿米卡星大多数细菌敏感。结论结论COPD患者的致病菌仍以革兰阴性菌为主,不动杆菌属、铜绿假单胞菌、肺炎克雷伯菌为主要病种,细菌耐药性明显增强。了解病原菌分布特点及耐药性监测指导临床合理使用抗生素。
Objective To observe characteristics of pathogenic bacteria in the elderly patients with COPD. Methods In 238 elderly patients with COPD, Isolation and culture of sputum was done, and drug sensitive test was performed with MIC. Results In 500 pathogenic bacteria, there were 487gram-negative bacteria （ 97.4% ）, included acinetobacter, pseudomonas aeruginosa and kebsiella pneumoniae. The drug sensitive test showed that bacterial drug resistance strenghtened, but bacteria were sensitive to imipenem,ciprofloxacin and amikacin. Conclusion The main pathogenic bacteria in patients with COPD is gram-negaative bacteria,which will be helpful to administrate antibiotics rationally in clinic.
出处
《临床合理用药杂志》
2009年第12期21-22,共2页
Chinese Journal of Clinical Rational Drug Use
