摘要
目的：阐明结核－聚合酶链反应（ＴＢ－ＰＣＲ）在诊断结核性胸腔积液中的作用。方法：以胸膜活检病理结果为标准，总结了１１８例胸腔积液ＴＢ－ＰＣＲ的检测结果，并与结核菌涂片、培养两种方法进行了对比。结果：ＴＢ－ＰＣＲ、涂片、培养三种方法的阳性率分别为３３％，０和５％，前者高于后两者（Ｐ＜０．００１）。但ＴＢ－ＰＣＲ的假阴性率较高（６７％）。结论：用ＴＢ－ＰＣＲ法诊断结核性胸腔积液的价值有限。
Objective: To elucidate the value of tuberculosis polymerase chain reaction (TBPCR)in the diagnosis of tuberculous pleural effusion. Methods:TBPCR was parformed in 118 patients with pathologic diagnosis of tuberculosis (TB), and compared with pleural fluid smear and culture. Results: The positive rate of the three methods was 33%,0,and 5% respectively. The positive rate of TBPCR was higher than that of smear and culture (P<0001) .But the false negative rate of TBPCR was higher (67%). Conclusion: The value of TBPCR in the diagnosis of tuberculous pleural effusion was limited. Pleural biopsy is the first choice.
出处
《新医学》
1998年第7期349-350,共2页
Journal of New Medicine
关键词
结核性
胸腔积液
聚合酶链反应
Tuberculosis Pleural effusion Polymerase chain reaction Pleural biopsy
