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聚合酶链反应快速检测结核杆菌 被引量:1

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摘要 早期诊断是结核病防治的主要手段之一,采用聚合酶链反应(PCR)技术检测临床标本中结核杆菌DNA,共检测197例,阳性83例,阴性114例,并对提高PCR检测敏感性。
作者 付娟 张彦梅
出处 《山西医科大学学报》 CAS 1998年第2期191-191,共1页 Journal of Shanxi Medical University
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同被引文献13

  • 1结核病诊断细菌学检验规程[J].中国防痨杂志,1996,18(1):28-31. 被引量:803
  • 2LEE K W,LEE M,JUNG K S.Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Korea[J].J Korean Med Sci,2001,16(5):537-543.
  • 3SCORPIO A,LINDHOLM-LEVY P,HEIFETS L,et al.Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis[J].Antimicrob Agents Chemo-ther,1997,41:540-543.
  • 4SREEVATSAN S,PAN X,ZHANG Y,et al.Mutations associated with pyrazinamide resistance in pncA of Mycobacterium tuberculosis complex organisms[J].Antimicrob Agents Chemother,1997,41:636-640.
  • 5HOE L,OSEI-HYIAMAN D,ZHANG Z,et al.Molecular characterization of pncA gene mutations in Mycobacterium tuberculosis clinical isolates from China[J].Epidemiol Infect,2000,124(2):227-232.
  • 6LEE A S,TANG L L,LIM I H,et al.Characterization of pyrazinamide and of loxacin resistance among drug resistant Mycobacterium tuberculosis isolates from Singapore[J].Int J Infect Dis,2002,6(1):48-51.
  • 7BISHOP K S,BLUMBERG L,TROLLIP A P,et al.Characterization of the pncA gene in Mycobacterium tuberculosis isolates from Gauteng,South Africa[J].Int J Tuberc Lung Dis,2001,5(10):952-957.
  • 8MESTDAGH M,REALINI L,FONTEYNE P A,et al.Correlation of pncA sequence with pyrazinamide resistance level in BACTEC for 21 Mycobacterium tuberculosis clinical isolates[J].Microb Drug Resist,2000,6(4):283-287.
  • 9BAMAGA M,WRIGHT D J,ZHANG H.Selection of in vitro mutants of pyrazinamide-resistant Mycobacterium tuberculosis[J].Int J Antimicrob Agents,2002,20(4):275-281.
  • 10BAMAGA M,ZHANG H,WRIGHT D J.New mutations in pncA of in vitro selected pyrazinamide-resistant strains of Mycobacterium tuberculosis[J].Microb Drug Resist,2001,7(3):223.

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