摘要
通过对老年高血压病有无左室肥厚患者各20例,进行性别、年龄配对后,观察其中医血瘀证积分与血液流变学指标的变化,以及血瘀证与左室肥厚的关联程度。结果显示:①有左室肥厚(LVH)者血瘀证积分高于无左室肥厚(NLVH)者(P<0.05);血瘀证与LVH关联密切(OR=4.5);②LVH者存在全血粘度(低切)、血浆粘度、纤维蛋白原、血小板聚集率增高为主;NLVH者存在血浆粘度、血小板聚集率增高为主。提示:①血液粘度增高是引起外周阻力增高的原因之一,后者与LVH形成有关;血瘀是影响LVH形成的一种中医病理因素,其积分变化可以部分反映老年高血压病引起LVH改变的进程。②中药活血化瘀对防治老年高血压病左室肥厚可能有益。
20 cases of senile hypertension patients with or without left ventricular hypertrophy (LVH) were investigated for observing the correlation between TCM blood stasis and blood rheology and between blood stasis and LVH.The result showed that, 1.the integral of TCM blood stasis in LVH group was higher than that in non-LVH group(P<0.05 ). 2.The whole blood viscosity,plasma in LVH group while mainly the plasma viscosity and platelet aggregation rate rose in non-LVH group.It indicates that, 1.the higher blood viscosity is peripheral resistance which is related to the occurrence of LVH.The blood stasis is one of the TCM pathogenic factors which the change of the integral partly reflect the process of LVH. 2.The TCM agents for activating blood removing stasis might be beneficial for the prevention and treatment of LVH in senile hypertension.
出处
《福建中医学院学报》
1998年第2期7-9,共3页
Journal of Fujian College of Traditional Chinese Medicine
关键词
高血压
心脏扩大
血瘀
血液流变学
hypertension/blood
cardiac enlargement/blood
blood stasis
blood rheology