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老年高血压病左室肥厚与中医血瘀证积分及血液流变学的关系 被引量:15

Relationship Among Left Ventricular Hypertrophy,Integral of TCM Blood Stasis & Blood Rheology in Senile Hypertension
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摘要 通过对老年高血压病有无左室肥厚患者各20例,进行性别、年龄配对后,观察其中医血瘀证积分与血液流变学指标的变化,以及血瘀证与左室肥厚的关联程度。结果显示:①有左室肥厚(LVH)者血瘀证积分高于无左室肥厚(NLVH)者(P<0.05);血瘀证与LVH关联密切(OR=4.5);②LVH者存在全血粘度(低切)、血浆粘度、纤维蛋白原、血小板聚集率增高为主;NLVH者存在血浆粘度、血小板聚集率增高为主。提示:①血液粘度增高是引起外周阻力增高的原因之一,后者与LVH形成有关;血瘀是影响LVH形成的一种中医病理因素,其积分变化可以部分反映老年高血压病引起LVH改变的进程。②中药活血化瘀对防治老年高血压病左室肥厚可能有益。 20 cases of senile hypertension patients with or without left ventricular hypertrophy (LVH) were investigated for observing the correlation between TCM blood stasis and blood rheology and between blood stasis and LVH.The result showed that, 1.the integral of TCM blood stasis in LVH group was higher than that in non-LVH group(P<0.05 ). 2.The whole blood viscosity,plasma in LVH group while mainly the plasma viscosity and platelet aggregation rate rose in non-LVH group.It indicates that, 1.the higher blood viscosity is peripheral resistance which is related to the occurrence of LVH.The blood stasis is one of the TCM pathogenic factors which the change of the integral partly reflect the process of LVH. 2.The TCM agents for activating blood removing stasis might be beneficial for the prevention and treatment of LVH in senile hypertension.
出处 《福建中医学院学报》 1998年第2期7-9,共3页 Journal of Fujian College of Traditional Chinese Medicine
关键词 高血压 心脏扩大 血瘀 血液流变学 hypertension/blood cardiac enlargement/blood blood stasis blood rheology
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参考文献3

  • 1李小鹰,韦立新,陶国枢,刘国仗,王士雯,黄宛.高血压病左室肥厚患者尸检冠状动脉粥样硬化及心脏事件的发生率[J].中华心血管病杂志,1995,23(3):191-194. 被引量:25
  • 2王序,韩桂秋,李荣芷,潘竞先,陈雅研,何云庆,涂馥,王邠,Leeyuan Huang,Cindy Lee,Maria Sandrino,M. N. Chang,T.Y. Shen.现代生物分析法对常用中药的筛选研究[J]北京医科大学学报,1986(01).
  • 3中国中西医结合学会活血化瘀研究学会(大陆)等.海峡两岸活血化瘀与喘证方药研究[M]中国医药科技出版社,1994.

二级参考文献1

  • 1刘国仗,实用高血压学,1993年

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