摘要
目的探讨肺源性心脏病（肺心病）急性加重期患者甲状腺功能的变化特点及意义。方法肺心病急性加重期200例作为观察组，同期健康体检者200例作为对照组，观察正常甲状腺病态综合征（ESS）发生情况，对比对照组与观察组中存活、病死患者的甲状腺素水平，ESS者治疗前后甲状腺素检查结果、ESS与死亡的关系。结果肺心病急性加重期ESS发生率42．5％（85／200）；观察组人院时T3、FT3低于对照组；观察组中存活和病死比较，TSH无显著性差异外、病死患者T3、FT3、T4、FT4均低于存活患者（P〈0．05）；原发病治疗好转后，甲状腺素可恢复或接近正常；发生ESS病死率30．59％。高于未发生变化的病死率13．04％。结论血清甲状腺素水平变化反映了肺心病急性加重期患者的全身状态和严重程度，动态检测血清中甲状腺素水平可以预测肺心病的发展和转归。
Objective To investigate pulmonary heart disease acute exacerbation of changes in the characteristics of thyroid function and significance. Methods Pulmonary heart disease with acute exacerbation of 200 cases as the observation group,in the same period 200 cases of healthyas control group, observation euthyroid sick syndrome （euthyroid sick syndrome,ESS） occurred, compared the observe and control groups, observer group in the survival group died with the group,ESS thyroid hormone treatment before and after the test resuhs,ESS and death. Results Pulmonary heart disease with acute exacerbation of ESS incidence of 42. 5% （85/200） ;section observe the admission T3 , FT3 lower than the control group;observer group in the survival group died and TSH group no significant difference,the group died T3 ,FT3 ,T4 ,FT4 were lower than the survival group（P 〈0. 05） ;improvement in the treatment of primary disease, thyroid hormone, or return to near normal; ESS mortality occurred in 30. 59% higher than a change of 13.04% mortality rate. Conclusion Serum thyroid hormone levels to reflect changes in the pulmonary heart disease in patients with acute exacerbation of the state of the body and severity of the dynamic serum levels of thyroid hormone can observe the development of pulmonary heart disease and prognosis.
出处
《中国基层医药》
CAS
2009年第5期821-822,共2页
Chinese Journal of Primary Medicine and Pharmacy
