摘要
研究表明,在有机小分子二甲基甲酰胺(DMF)的调控作用下Keggin型多金属氧化物在水溶液中形成规则的纳米立方体,随温度改变该纳米立方体转变为空心立方结构.该多金属氧化物纳米立方体可以与朊蛋白(PrPC)相互作用,产生显著的光散射信号增强,且增强程度在3.36～840ng·mL-1范围内与朊蛋白浓度呈线性关系.
It was found in this contribution that Keggin-type of polyoxometalates nanocubes could be formed in aqueous medium under the adjustment of dimethylformamide （DMF）, which could be changed from solid nanocubes to hollow ones with the increasing of temperature. Further investigations showed that this Keggin-type of polyoxometalates nanocubes can specifically interact with prion protein, and the light scattering signals were enhanced in proportional to the content of priori in the range of 3.36-840 ng.mL^-1.
出处
《中国科学（B辑）》
CSCD
北大核心
2009年第6期495-500,共6页
Science in China(Series B)
基金
科技部国家重大科学研究计划(批准号:2006CB9331003)资助
