期刊文献+

奥曲肽治疗非静脉曲张性上消化道大出血疗效观察

暂未订购
导出
摘要 目的:观察奥曲肽联合泮托拉唑对非静脉曲张性上消化道出血的疗效。方法:将60例非静脉曲张性上消化道出血患者分成对照组(30例)和观察组(30例),两组均给予泮托拉唑静脉注射,对照组加用止血药物(立止血静脉注射、止血定、止血芳酸静脉滴注),观察组加用奥曲肽0.1 mg静脉注射,两组持续用药72h后,观察两组止血效果。结果:观察组和对照组12h止血显效率分别为90.4%和71.7%,24h小时止血显效率分别为94.2%和78.3%,48h小时止血显效率分别为98.1%和93.5%。两组比较差异有显著性P<0.01。结论:奥曲肽合联合泮托拉唑治疗非静脉曲张性上消化道大出血的疗效明显优于泮托拉唑组,其疗效肯定。
作者 刘万福
出处 《现代医药卫生》 2009年第14期2152-2152,共1页 Journal of Modern Medicine & Health
  • 相关文献

参考文献2

二级参考文献26

  • 1[1]Anonymous. Pantoprazole--a third pump inhibitor[J]. Drug Ther Bull, 1997,35(2):93-94.
  • 2[2]Sachs C. Proton pump inhibitors and acid-related disease[J]. Pharmaco Therapy, 1997,17(1):22-37.
  • 3[3]Bliesath H, Huber R, Hartmaun H, et al. Dose linearity of the phar-macokinetics of the new H+/K+-ATPase inhibitor pantoprazole after single intravenous administration [J]. J Clin Pharmacol Ther, 1996,34(Suppl 1):18-24.
  • 4[4]Huber R, Hartmaun M, Bliesath H, et al. Pharmacokinetics of panto-prazole in man[J]. J Clin Pharmacol Ther, 1996,34((Suppl 1): 7-16.
  • 5[5]Wurzer H, Sohutze K, Bethke T, et al . Efficacy and safety of panto-prazole in patients with gastroesophageal reflux disease using in intravenous-oral regim[J]. Hepatogastroent, 1999,46:1809-1815.
  • 6[6]Paul J, Metz D, Marton P, et al. Pharmacodynamic equivalence of oral and iv pantoprazole in GERD patients[J]. Am J Gastroenterol, 1998,93:1622, Abstract.
  • 7[7]Metz D C, Forsmark C E, Soffer E, et al. Zollinger-Ellison syndrome patients can replace oral proton pump inhibitors with intravenous pantoprazole without losing control of acid output[N]. Paper Presented at Digestive Disease Week. 1999-05-16(19).
  • 8[8]Koop H, Kuly Schepp W, Dammann H G. Comparative trial of panto-prazole and ranitidine in the treatment of reflux esophagitis results of a German multicenter study[J]. J Clin Gastroenterol, 1995,20(3):192-195.
  • 9[9]Bochenek W. Pantoprazole heals erosive esophagitis more effectively and provides greater symptomatic relief than placebo or nizatidine in gastro-esophageal reflux disease patients[N]. Paper Presented at Digestive Disease Week. 1999-05-16(19).
  • 10[10]Corinaldesi R, Valentini M, Belaiche J, et al. Pantoprazole and ome-prazole in the treatment of reflux esophagitis :a European multicentre study[J]. Aliment Pharmacol Ther, 1995,9:667-671.

共引文献40

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部