摘要
用阈值模式中各级亲属预期发病率的公式和Falconer计算多基因的遗传率,对157例非特异性精神发育迟滞(NSMR)的家系进行了多基因遗传分析,结果表明:在NSMR中存在着多基因的主基因作用,遗传率为(872±41)%。
By using the formula for estimating the expected incidence in the relations of affected individuals and polygenic inheritance of Falconer,157 families of nonspecific mental retardation were analysed. The results showed that NSMR had polygenic inheritance with majorgene effect and its heritability was (872±41)%
关键词
智力迟钝
遗传病
精神发育迟滞
多基因遗传
mental retardation
hereditary diseases
mental retardation,nonspecific
genetics,medical