摘要
目的探讨连续性血液净化对重症急性胰腺炎血浆炎症因子的影响.方法对18例重症急性胰腺炎患者,在常规治疗基础上应用连续性血液净化治疗,观察治疗前后患者血浆炎症因子TNF-α、IL-6、IL-8和CRP水平.结果应用连续性血液净化治疗后血浆炎症因子TNFα、IL-6、IL-8和CRP水平明显下降,与治疗前比较差异有统计学意义(P<0.05).结论连续性血液净化能降低重症急性胰腺炎患者血浆炎症因子TNF-α、IL-6、IL-8和CRP水平,减轻炎症反应,可成为治疗重症急性胰腺炎的重要手段.
Objective To explore the effect of continuous blood purification on plasma inflammatory mediators levels of patietns with severe acute pancreatitis. Methods 18 patietns with severe acute pancreatitis were given continuous blood purification during regular treatment. Plasma levels of TNF-α, IL-6, IL-8 and C reactive protein （CRP） were detected before and after continuous blood purification treatment. Results Compared with before treatment, plasma levels of TNF-α, IL-6, IL-8 and C reactive protein） CRP） decreased significantly after continuous blood purification treatment （P 〈 0.05）. Conclusion Continuous blood purification can decrease plasma levels of TNF-α, IL-6, IL-8 and CRP of patients with severe acute pancreatitis, and may become an important therapeutic method for severe acute pancreatitis.
出处
《昆明医学院学报》
2009年第6期143-145,共3页
Journal of Kunming Medical College
关键词
连续性血液净化
重症急性胰腺炎
炎症因子
患者
Continuous blood purification
Severe acute pancreatitis
Inflammatory mediators
Patietnts
