摘要
微生物脂肽是一类具有很强表面活性和生物特性的生物表面活性剂。脂肽分子由亲水的肽链和疏水的脂肪烃链两部分组成,由于其特殊的化学组成和两亲性分子结构,脂肽类生物表面活性剂在医药、食品、化妆品、环境修复和微生物采油等领域有很好的应用潜力。表面活性素是一类典型的微生物脂肽化合物,这主要是因为它除了具有表面活性外,还具有抗菌、抗病毒等生物活性。表面活性和生物活性主要在界面处发生,并受到活性分子在亲水/疏水界面上的分子形态的影响。本文重点以表面活性素为评述对象,综述了近年来微生物脂肽在气/液界面上分子形态的研究进展。
The microbial lipopeptides, which is an important kind of biosurfactants, possesses powerful surface activities and peculiar biological properties. The primary structure of the lipopeptides is mainly composed of a hydrophilic peptide moiety and a hydrophobic alkyl chain. Because of its chemical composition and amphiphi!ic behavior, the lipopeptides can be exploited in many fields such as pharmaceutics, food and cosmetic industries, environmental remediation and oil recovery. The surfactin, primarily renowned for its exceptional surface activities as well as biological properties, is one of the most active microbial lipopeptides. Surface-active and biological properties mainly occur at interfaces and are governed by the conformational state of molecules at hydrophobic/hydrophilic interfaces. This paper reviews the recent progress in molecular behavior of microbial lipopeptides represented by surfactin at the air/water interface.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2009年第6期1118-1123,共6页
Progress in Chemistry
基金
国家自然科学基金项目(No.50574040)
上海市科委项目(No.071607014)资助
关键词
微生物脂肽
表面活性素
气/液界面
分子形态
microbial lipopeptides
surfactin
air/water interface
molecular behavior
