摘要
按照国家对照品的研制指导原则,进行了头孢噻呋国家对照品的研制。通过稳定性研究,确定了盐酸头孢噻呋作为对照品原料,然后对所选取原料分别用元素分析、红外分光光度法和液相色谱法确证了头孢噻呋的结构。液相色谱法测定纯度为96.8%,含量赋值为87.5%。
According to guidelines for the establishment of national chemical reference standards, this article studied and prepared ceftiofur reference standards. Ceftiofur hydrochloride was selected as material resource of reference standards by research of stability. Then the experiment confirmed chemical structure by element analysis, IR and HPLC respectively. The purity was 96.8% by HPLC,and assigned content was 87.5%.
出处
《中国兽药杂志》
2009年第6期22-25,共4页
Chinese Journal of Veterinary Drug
基金
生物化学计量标准资源整合与共享体系建设项目资助
关键词
头孢噻呋
对照品
结构确证
纯度
含量
ceftiofur hydrochloride
reference standards
confirmation of chemical structure
purity
content
