摘要
目的探讨直肠癌伴肠梗阻的临床病理特征和预后。方法对手术治疗的398例直肠癌患者中的82例同时伴肠梗阻患者的临床资料进行总结,并分析预后的影响因素。结果手术治疗的398例直肠癌患者中,316例无肠梗阻,生存期为(104.494±4.076)个月,5年生存率为61.9%;82例伴有肠梗阻,生存期为(57.583±5.175)个月,5年生产率为34.9%。两组生存率差异有统计学意义(P=0.000)。COX回归模型分析结果显示,手术方式、辅助化疗均为保护性因素,而肠梗阻、大体类型、分化程度、TNM分期、远处转移均为危险因素。结论癌性肠梗阻严重地影响直肠癌患者的预后,术后化疗能改善直肠癌患者的预后。
Objective To investigate the clinieopathologic features and prognostic of rectal carcinoma with intestinal obstruction. Methods The clinieopathologieal data of 398 patients with rectal carcinoma with radical surgery were retrospectively reviewed. Results There were 316 cases without obstruction, whose survival time was （104. 494 ± 4. 076） months and survival rate of 5-year was 61.9%. The survival time of 82 cases with obstruction was （57. 583± 5. 175） months and the survival rate of 5-year was 34. 9%. There was remarkable significance of the indexes between the two groups （P〈0. 001）. Cox regression analysis indicated that surgical procedure and chemotherapy were protective factors, whereas obstruction, massive type of tumor, histological type, TMN stage and distant metastasis were adverse factors. Conclusion The malignant obstruction seriously influences the prognosis of patients with rectal carcinoma, But the chemotherapy after surgery plays an advantageous role in prognosis.
出处
《西部医学》
2009年第6期940-942,共3页
Medical Journal of West China
关键词
直肠肿瘤
肠梗阻
临床病理特征
预后
Rectal carcinoma
Intestinal obstruction
Clinicopathologieal feature
Prognosis
