摘要
测试了单味药麻黄、桂枝及麻黄+桂枝混合汤剂红外光谱,标示其吸收峰,并确认其归属。在麻黄+桂枝汤剂中保留了麻黄、桂枝单味药物汤剂中的某些成分,见麻黄+桂枝光谱1 205和1 074 cm-1处等;麻黄、桂枝光谱中的某些成分并未在麻黄+桂枝光谱中出现,见麻黄+桂枝光谱1 394和678 cm-1处等;在麻黄+桂枝汤剂光谱中,出现了新的吸收峰,见麻黄+桂枝光谱757和1 407 cm-1处等。同时,因吸收峰位置有所改变,说明各基团在麻黄、桂枝、麻黄+桂枝汤剂中所处的化学环境不同。在麻黄+桂枝汤剂中可能新生成了麻黄、桂枝单味药物汤剂中所没有的化学成分。麻黄+桂枝汤剂所包含的药物成分并非是单味麻黄、桂枝汤剂所含药物成分的简单相加。文章在研究麻黄+桂枝混合汤剂红外光谱的基础上提出了方剂光谱学的概念。
The infrared spectra of decoction of herba ephedra and ramulus cinnarnomi and the mixed decoction of herba ephedra ＋ ramulus cinnarnomi were tested. The change in the mixed decoction was discussed to study the relationship between herba ephedra and ramulus cinnarnomi after decoction. The results showed that some components of herba ephedra and ramulus cinnarnomi were retained in the mixed decoction of herba ephedra＋ramulus cinnarnomi, such as 1 205 and 1 074 cm^-1 , but some components that never appeared in the two component spectra increased, such as 1 394 and 678 cm^- 1. New absorption peaks were generated in the mixed decoction of herba ephedra ＋ ramulus einnarnomi, such as 757 and 407 cm^-1. It can be showed that there are differences in the chemistry environment of the various chemical groups in the three decoctions introduced above, and with the variation in absorption peak position, possibly some new chemical compositions were created. Medical ingredients in the decoction are not simply the addition of herba ephedra and ramulus einnarnomi, based on the studies of infrared spectrum of the mixed decoction of herba ephedra ＋ ramulus cinnarnomi, and the new notion of prescription spectroscopy was proposed.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2009年第7期1847-1850,共4页
Spectroscopy and Spectral Analysis
基金
国家自然科学基金项目(60711120031,60778046)
厦门大学固体表面物理化学国家重点实验室项目资助
关键词
方剂光谱学
红外光谱
麻黄
桂枝
汤剂
复方配伍
Recipe＇s spectroscopy
Infrared spectroscopy
Herba ephedra
Ramulus cinnarnomi
Prescription of chinese material mediea
Compound compatibility
