摘要
本研究测量了生后21天～6个月S.D雌性大鼠游离心肌细胞的体积、长度、横切面积、表面积、宽度和厚度,并对心肌细胞生长的形态学特点进行了观察。 1.正常心肌细胞的生长,是由于细胞的长度和横切面积的增加,从而使心肌细胞体积增大。随着心肌细胞的肥大性生长,细胞的横切面的形态也发生了变化。 2.心肌细胞横切面积的长轴,随心肌细胞体积的增加而逐渐增大;其短轴则增长较慢。从而导致心肌细胞体积增大,心肌细胞不断变宽,这种横向性生长方式是正常心肌细胞生长的一个特点。本文的结果提示,寻找并消除刺激心肌细胞横向增长的因素,对预防和治疗因心肌细胞肥大而产生的心脏疾病,可能具有重要意义。
The cell volume, length, cross-section area, surface area, width and thickness of isolated cardiac myocytes were measured by using of a new computer system of coulter channelyzer and avias eye imaging analysis system. The rats, 3 weeks to 24 weeks in age after birth, were performed thoracic operation the morphological growth characteristics of isolated cardiac myocytes were observed.1. Physiological growth of normal cardiac myocytes was due to increase in cell volume, i. e. the cell length and cross-section area were enlarged. In the mean time, the changes in cross-section shape of myocytes happened when the myocytes growing.2. The major axis of cross-section area of myocytes was enlarged but the minor cross-section diameter did not show any more changes. So that, the growth lead to the cardiac myocytes be flattened in shape. The flattened growing pattern was one of the characteristics of normal growing myocytes. It might be very significant for the clinicians to eliminate the factors which would stimulate myocytes to be enlarged in cell width, and to treat and to prevent the heart disease.
出处
《解剖学报》
CAS
CSCD
北大核心
1990年第3期242-247,共6页
Acta Anatomica Sinica
关键词
心肌细胞
生长
形态学
Isolated myocyte
Myocyte growth
Morphological characteristic
