摘要
烧伤后早期缺血缺氧损害难以避免，是引起严重烧伤并发症和死亡的最重要原因。早在20世纪60年代，人们已发现严重烧伤休克期心功能减退的现象。20世纪80年代以前，人们将其归咎于烧伤后毛细血管通透性增加使血容量显著减少，导致回心血量减少；以后则认为还与心肌抑制因子等的作用有关。
A series of studies demonstrated that myocardial damage and cardiac dysfunction occur immediately after severe burn even before the intervention of significant reduction in blood volume as a result of increased capillary permeability. Because the heart is the power organ of the circulation, such myocardial damage and cardiac dysfunction lead not only to cardiac deficiency, it is also a precipitating factor of burn shock and ischemic/hypoxic injury. Therefore, we nominate this phenomenon as ＂ shock heart＂. New measures including ＂ volume replacement＂ plus ＂ dynamic support＂ proposed according to this new recognition is of important clinical significance for burn shock resuscitation and prevention and treatment of ischemic/hypoxic injury, as well as reducing organ complications resulting from insufficient or excessive fluid resuscitation during early postburn stage.
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2009年第3期161-163,共3页
Chinese Journal of Burns
关键词
烧伤
休克心
缺血缺氧
防治
Burns
Shock heart
Hypoxia-ischemia
Prevention and treatment
