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免疫营养对外科脓毒症的治疗价值 被引量:1

Application of immunonutrition in patients with severe sepsis
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摘要 目的:研究免疫营养对外科脓毒症患者APACHE评分的影响。方法:60例外科脓毒症患者随机分成研究组和对照组各30例。研究组为免疫营养组,对照组为常规营养组。两组均给予常规外科治疗,并于术后第1天开始给予静脉营养治疗7d,其中研究组静脉应用谷氨酰胺,比较两组APACHE评分的变化。结果:两组治疗后APACHE评分均下降,研究组较对照组下降更为明显(P<0.05)。结论:谷氨酰胺增强的肠外营养能减轻外科脓毒症患者病情的危重程度,改善预后。 Objective:To evaluate the treatment of immunonutrition in patients with severe sepsis. Methods:60 patients with severe sepsis were observed in this study. They were divided into immunonutrition group and control group randomly. All patients were treated with routine surgical treatment combined with parenteral nutrition and observed for 7 days. 30 cases in immunonutrition group were treated with glutamine and another 30 cases in control group without glutamine, and scores of acute physiology and chronic health evaluation (APACHE Ⅱ )were analysed respectively. Results :After a week of nutritional support, the score of APACHE Ⅱ decreased significantly in two groups(P〈0. 05), and the decrease in immunonutrition group was more obvious than that in control group (P〈0. 05). Conclusion: Gin-intensified parenteral nutrition can resume the function of cells and organs ,and reduce the severity of the sepsis as well as improve the prognosis.
出处 《陕西医学杂志》 CAS 2009年第6期665-666,共2页 Shaanxi Medical Journal
基金 江西省科技成果重点推广项目(2007) 江西省卫生厅科技计划项目(20071024)
关键词 脓毒症 肠外营养 免疫营养 谷氨酰胺 Sepsis Parenteral nutrition Immunonutrition Glutamine
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