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新生儿血培养的菌谱调查及耐药性分析 被引量:7

Investigation of bacterial spectrum and analysis of drug resistance after neonatal blood culture
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摘要 目的:了解我院新生儿血培养病原菌的分布及耐药性分析。方法:法国生物梅里埃公司的BacT/A lert3D进行血液培养,菌株鉴定采用法国生物梅里埃公司的VITEK 60分析仪,药敏试验采用K-B法。结果:新生儿血培养中革兰阳性球菌占85.7%,凝固酶阴性的葡萄球菌(CNS)占73.6%,其中,表皮葡萄球菌占33%,溶血葡萄球菌占20.8%,其它凝固酶阴性的葡萄球菌占19.8%,革兰阴性杆菌只占11%。结论:CNS是引起新生儿败血症的主要病原菌,苯唑西林耐药凝固酶阴性的葡萄球菌占88%,对此类菌引起的感染宜首选万古霉素、力奈唑烷、利福平、喹奴普汀?达福普汀。 Objective: To study the pathogen distribution and antibiotic resistance after neonatal blood culture in our hospital. Methods:Blood was cultured in BacT/Alert3D of Bio - Merieux of France. The clinical isolates were identified by VITEK - 60 of Bio - Merieux of France. Antibiotic susceptive test was done by Kirby - Bauer method. Results : In newborn blood culture gram - positive cocci accounted for 85. 7% , Coagulase negative Staphylococcus (CNS) for 73. 6% , which accounted for 33% of Staphylococcus epidermidis, Staphylococcus hemolysis accounted for 20. 8%. The other coagulase - negative Staphylococcus accounted for 19. 8%, gram -negative bacilli account for only 11%. Conclusion: CNS is the main cause of neonatal sepsis pathogens, methicillin - resistant coagulase - negative Staphylococcus accounted for 88% . Curing infections caused by of these bacteria. Quinupristin/Dalfopr, vancomycin, rifampicin, and Linezolid should be of the first choice.
出处 《中国卫生检验杂志》 CAS 2009年第5期1091-1092,共2页 Chinese Journal of Health Laboratory Technology
关键词 新生儿 病原菌 耐药性 Newborn Pathogens Resistance
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  • 1张智洁,王林茹,王群,刘勇,徐秀杰.儿科败血症致病菌分布及耐药分析[J].中国医科大学学报,2002,31(6):476-478. 被引量:13
  • 2Waheed M, laeeg A, Magbool S. The etiology of neonatel sepsis and patterns of antibiotics resistance[ J]. J Coil Physic Surg Pak, 2003,13 (8) :52.
  • 3Patrick R Murray.徐建国,梁国栋,邢来君,等译.Manual of Clinical Microbiology[M].第7版.北京:科学出版社,2005:77-136.

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