摘要
CASE按4.0g/kg,8.0g/kg给小鼠灌胃给药,每天1次,连续7d,可明显延长正常小鼠及“肾阳虚”小鼠的游泳时间,亦能增加小鼠免疫器官重量,提高网状内皮系统的吞噬功能。若连续灌胃28d,可使亚急性衰老小鼠血中过氧化脂质(LPO)含量及心肌脂褐质含量明显降低,并明显提高皮肤羟脯氨酸含量。提示CASE具有抗衰老作用。
おntiaging actions of Compound Acanthopanax Senticosus Extracts(CASE) were studied and the results indicated that CASE(4.0 and 8.0 g/kg,ig×7d)might prolong sinificantly swiming time in normal and renal deficiency mice and also increase the weight of immune organs and enhance the phagocytosis of reticuloendothelal system in normal mice.In addition,CASE(8.0 g/kg,ig×28d)might decrease serum lipoperoxides and myocardial lipofuscin contents and raise skin hydroxyproline content in subacute aging model mice.It is suggested that CASE have antiaging action.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
1998年第3期170-171,共2页
Chinese Journal of Gerontology