期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

围手术期认知功能障碍的影响因素

暂未订购
导出
摘要 围手术期认知功能障碍是由多种因素造成的。患者性别、文化背景、睡眠与饮食等生活习惯是发生认知功能障碍的基本因素。遗传因素如基因及受体多态性成为该类疾病的易发因素。应激反应及激素水平的变化、高血压、慢性阻塞性肺疾病(COPD)、糖尿病成为促发因素。围手术期的医疗处理,如麻醉药物及麻醉方法的选择;手术种类、大小以及方式;围手术期呼吸、循环等生命体征的调控均可直接影响患者的认知功能状态,决定患者愈后的生存质量。同时,对于相关的影响因素,如药物、体温、住院、血红蛋白、术后镇痛等,也进行了必要的阐述。其目的在于早期发现、早期干预发生认知功能障碍的各种因素,以便延缓或阻止认知功能障碍的发生与发展,提高医疗水平,改善患者的生存质量。
作者 陈斌
机构地区 川北医学院附属医院麻醉科
出处 《川北医学院学报》 CAS 2009年第3期211-217,共7页 Journal of North Sichuan Medical College
关键词 围手术期 认知功能障碍 影响因素
分类号 R614 [医药卫生—麻醉学]
  • 相关文献

参考文献68

  • 1Miller K, Asbury A J, Murray GD, et al. Pre-existing cognitive impairment as a factor influencing outcome after cardiac surgery [ J]. BrJ Anaesth, 2001, 86 ( 1 ) :63 -67
  • 2Mathuranath PS, Geoge A,Chefian PJ,et al . Effects of age, education and gender on verbal fluency [J]. J Clin Exp Neuropsychol, 2003, (25) : 1057 - 1064
  • 3Lee T, Yuen K, Chen C. Normative data for neuropsychological measures of fluency, attention and memory measures for Hong Kong Chinese [J].J Clin Exp Neuropsychol,2002, (24) : 615 -632
  • 4Georgopoulos AP,Whang K, Georgopoulos MA,et al. Functional magnetic resonance imaging of visual object construction and shape discrimination : relations among task, hemispheric laterulization and gender [J]. J Cogn Neurosci,2001, (13) : 72 -89
  • 5Dodds C, Browne SM,Wade DT, et al. Postoperative hypoxia is a contributory factor to cognitive impairment after cardiac ,surgery [ J]. J Thorae eardiovasc surg, 2003, 126 (4) :1061 - 1064
  • 6Rasmussen LS, Steentoft A, Rasmussen H, et al. Benzodiazepines and postoperative cognitive dysfunction in the elderly[ J]. Br J Anaesth, 1999,83(4) : 585 -589
  • 7Stratmann G, Sail JW, May LD, et al . Isoflurane Differentially Affects Neurogenesis and Long-term Neurocognitive Function in 60-day-old and 7-day-old rats [ J ]. Anesthesiology,2009,110 (4) : 834 - 48
  • 8Arehila A, Moreno S. Neuropsychological test performance in Auuaeo Indians : an exploratory study [ J]. J Int Neuropsyehol Soc,2001,(7 ) : 510 -515
  • 9Small GW, La Rue A, Komo S, et al. Predictors of cognitive change in middle-aged and older adults with memory loss[ J]. Am J Psychiatry, 1995, 152(12) : 1757-1764
  • 10Roth T, Costae Slilva JA, Chase MH. Sleep and cognitive (memory) function : research and clinical perspectives [ J]. Sleep Med, 2001 : (2) : 379 - 387

二级参考文献41

  • 1张世仪,何利明,张敏磊,付建军.一种脑损伤所致认知障碍的动物模型[J].中国康复医学杂志,1993,8(5):196-198. 被引量：8
  • 2付建军 张世仪.Org2766和山茛菪碱慢性给药对大鼠回避反应学习记忆的影响[J].基础医学与临床,1992,12:376-376.
  • 3陈勤.抗衰老实验研究方法[M].北京:中国医药科技出版社,1996.147-149.
  • 4Ptmjasawadwong Y, Boonjeungmonkol N, Phongchiewboon A. Bispectral index for improving anesthetic delivery and postoperative recovery[J]. Anesth Analg,2008,106(4) : 1326.
  • 5Rasmussen L.S, Larsen K, Houx P, et al. The assessment of postoperative cognitive function[J]. Acta Anaesthesiol Scand, 2001,45(3) :275.
  • 6Borroni B,Colciaghi F,Caltagirone C,et al.Platelet amyloid precursor protein abnormalities in mild cognitive impairment predict conversion to dementia of Alzheimer type:a 2-year follow-up study[J].Arch Neurol,2003,60(12):1740
  • 7Andreasen N,Vanmechelen E,Vanderstichele H,et al.Cerebrospinal fluid levels of total-tau,phospho-tau and A beta 42 predicts development of Alzheimer′s disease in patients with mild cognitive impairment[J].Acta Neurol Scand Suppl,2003,179:47
  • 8Pratico D,Clark CM,Liun F,et al.Increase of brain oxidative stress in mild cognitive impairment:a possible predictor of Alzheimer disease[J].Arch Neurol,2002,59(6):972
  • 9Larrieu S,Letenneur L,Orgogozo JM,et al.Incidence and outcome of mild cognitive impairment in a population-based prospective cohort[J].Neurology,2002,59(10):1594
  • 10Catani M,Cherubini A,Howard R,et al.H-MR spectroscopy differentiates mild cognitive impairment from normal brain aging[J].Neutopreport,2001,12:2315

共引文献55

川北医学院学报
2009年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部