摘要
目的利用多层CT灌注成像探讨肝硬化血流灌注变化及与门静脉径线的相关性。方法肝硬化31例，选取第一肝门层面作为CT灌注扫描靶层面，采用彩色灌注图法获得各肝脏灌注参数并对门静脉径线进行均值测量；30例正常人作对照组。结果正常组与肝硬化组肝脏灌注参数分别为：肝动脉灌注量（HAP）（24．80±5．84）、（19．49±7．30）ml／（min·100ml），门静脉灌注量（PVP）（104．91±21．70）、（79．17±23．05）mL／（min·100ml），总肝灌注量（TLP）（129．90±25．19）、（98．67±22．74）ml／（min·100ml），2组比较，差异均有统计学意义（P〈0．05）；肝动脉灌注指数（HPI）（19．13±3.33）％、（20．61±8．56）％，2组比较，差异无统计学意义（P〉0．05）。肝硬化患者的TLP与门静脉前后径呈负相关（r=-0．46，P〈0．05）。结论多层螺旋CT灌注成像是评价肝硬化血流灌注变化的一种有效的非创伤性的检查方法。肝硬化时门静脉前后径的变化反映其肝脏血流灌注状况。
Objective To discuss correlation of hemodynamic changes and portal vein diameter with multi-slice spiral CT perfusion imaging in liver cirrhosis. Method 31 cases liver cirrhosis were enrolled in this study. The first porta hepatis were selected for target lay of CT perfusion scan. Liver perfusion parameters were obtained by color perfusion map method. Right to left diameter and occipitofrontal diameter of portal vein were measured. 30 cases of normal persons were used as control group. Result Hepatic arterial perfusion （HAP） in liver perfusion parameters of normal group and liver cirrhosis group were （24. 80 ± 5.84） and （ 19.49 ± 7. 30） m]/（ min ± 100ml） respectively. Portal venous porfusion （PVP） were （ 104. 91 ± 21.70 ） and （79. 17 ± 23. 05 ） ml/（ rain ± 100nd ）, total liver porfusion （TLP） were （129.90 ± 25. 19） and （98.67 ± 22. 74）mL/（ min ± 100ml）. There were statistically significant difference between the two groups （ P 〈 0. 05 ）. Hepatic perfusion index （HPI） were （ 19. 13 ± 3.33 ） % and （20.61 ± 8. 56） %, which had no statistically significant difference with the other two groups （ P 〉 0. 05 ）. Conclusion Multi-spiral CT perfusion imaging is an effectively noninvasive method to evaluate the hemodynamic changes of liver cirrhosis. Occipitofrontal diameter of portal vein with liver cirrhosis can reflect the state of liver hemodynamics.
出处
《中国医师杂志》
CAS
2009年第5期606-608,共3页
Journal of Chinese Physician
