摘要
目的:观察阿托伐他汀对稳定型心绞痛患者C反应蛋白(CRP)的影响。方法:65例稳定型心绞痛患者随机分为对照组和阿托伐他汀治疗组。对照组给予阿斯匹林、β-受体阻滞剂、硝酸酯类等常规治疗,治疗组在常规治疗基础上给予阿托伐他汀20mg/d,疗程2周。分别在治疗前后观察和记录心绞痛发生的次数、心电图的改变,同时检测血脂和血清hs-CRP水平。结果:两组患者的心绞痛发生次数减少,心电图提示心肌缺血明显改善;治疗组血脂和hs-CRP较对照组明显下降(P<0.05)。结论:阿托伐他汀可明显降低稳定型心绞痛患者hs-CRP水平。
Objectlve ：To observe the effect of atorvastatin in treating stable angina pectoris.Methods：65 patients with stable angina peetoris were randomly divided into two groups.One group was treated with conventional therapy.Meanwhile,the other 33 patients in treatment group,on the basis of conventional therapy,were treated by atorvastatin 20 mg once a day.with a treatment course of 12 weeks for both groups.The outbreak of angina,change of electrocardiogram,level of blood fat and hs-CRP were observed before and after treatment.Results：In all cases, the outbreak of angina, change of electrocardiogram were improved ＇after treated for 12 weeks.The level of blood fat and hs-CRP were improved markedly.Conelusion：Atorvastatin could significantly decrease the local inflammation of acute coronary syndrome.
出处
《现代医药卫生》
2009年第11期1610-1612,共3页
Journal of Modern Medicine & Health
