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肿瘤血管生成与结肠癌浸润转移的关系 被引量:6

Tumor angiogenesis correlated with metastasis in colon carcinoma.
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摘要 目的探讨结肠癌肿瘤血管形成与临床病理特征的关系及其是否可用于预测结肠癌浸润转移。方法应用SP法测定42例结肠癌石蜡切片微血管数量。结果伴淋巴结转移、远处转移及DukesB,C期病人,微血管计数高于相应无转移及DukesA期病人。结论微血管计数测定血管形成可作为预测结肠癌转移潜能的标志。 Objective To investigate the correlation between the tumor angiogenesis and the clinicopatho-logyic characteristics and determine whether tumor angiogenesis can be used as an indicator for invasion and metastasis in colon cancer. Methods Microvessel counts (MVC)in paraffin-embedded sections from 42 patients with primary colon cancer were measured by SP method. Results MVC in the patients with lymph node metastasis,distant metastasis,and Dukes B and C were significantly higher than those in the patients without metastasis and with Dukes A. Conclusion Angiogenesis expressed as MVC might be an indicator for predicting the metastasis potential of colorectal carcinoma.
出处 《中华实验外科杂志》 CAS CSCD 北大核心 1998年第4期308-309,共2页 Chinese Journal of Experimental Surgery
关键词 结肠肿瘤 血管形成 肿瘤转移 肿瘤浸润 Metastasis colon Carcinoma Angiogenesis
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  • 1Manfred Volm,Reet Koom?gi,Manfred Kaufmann,Jürgen Mattern,Gerd Stammler. Microvessel density, expression of proto-oncogenes, resistance-related proteins and incidence of metastases in primary ovarian carcinomas[J] 1996,Clinical & Experimental Metastasis(3):209~214

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