摘要
目的：观察左旋卡尼汀联合应用促红细胞生成素（EPO）治疗肾性贫血的疗效观察。方法：30例维持性血液透析患者随机分为两组，A组给予EPO及左旋卡尼汀治疗，B组给予EPO及等容积生理盐水作为对照，治疗前、后第4，8周测定血红蛋白及血细胞比容。结果：A组患者的血红蛋白及血细胞比容水平显著高于B组（P〈0．05），且A组的EPO平均用量明显少于B组（P〈0．05）。结论：左旋卡尼汀联合应用EPO可以改善肾性贫血，提高EPO疗效，可以减少EPO的用量。
Objective： To observ the clinical effect of L-carnitine plus erythropoietin （EPO） on nephritic anemia. Methods：Thirty maintenance hemodialysis patients were randomly divided into 2 groups. Group A were treated with L-carnitine plus EPO. Group B as the control group were treated with EPO plus same volum sodium. Hemoglobin （Hb） and hematocrit （Hct） levels were detected before and after treatmen. Results ：Compared with group B,Hb and Hct levels increased significantly in group A（P〈0. 05） ,and the average dosage of EPO in group A was significantly lower than that in group B（P〈0.05）. Conclusion ：L-earnitine could improve the effect of EPO in the treatment of patients with nephritic anemia and reduce the dosage of EPO.
出处
《临床医药实践》
2009年第5期329-331,共3页
Proceeding of Clinical Medicine
