摘要
目的评价血液回收用于脑膜瘤切除术中的安全性。方法选择1999年1月～2006年12月期间134例在北京天坛医院进行脑膜瘤切除手术的病人．进行最短为期12个月的术后随访。其中应用术中血液回收的病人89例（Ⅰ组），男性44例．女性45例；未应用血液回收的病人45例（Ⅱ组），男性21例，女性24例。两组术后平均随访期分别为25个月（12—58个月）及30个月（12～82个月）。通过头部影像学复查及包括胸片或胸透和腹部B超在内的全身体检，判断肿瘤是否复发或发生了颅外转移。结果Ⅰ组病人术中回输回收血液平均525ml（150～2000ml），有7例（7．9％）病人术中输入异体血液：Ⅱ组有11例（24．4％）病人术中输入了异体血液（P〈0．001）。随访期内，两组肿瘤Simpson Ⅰ级切除的病例中，分别有5例（7．6％）和4例（11．8％）复发（P=0．75）。两组术后均未发现肿瘤颅外转移者。结论血液回收用于脑膜瘤切除术中．尚未发现其导致的肿瘤颅外转移或增加复发。
Objective To assess the safety of intraoperative blood salvage in resection of meningioma. Methods A total of 134 patients were performed resection of meningioma in Beijing Tiantan hospital from January 1999 to December 2006, and followed up in a period of at least 12 months. Among the patients, 89 patients （group Ⅰ , male 44, female 45） received intraoperatively salvaged blood and 45 patients （group Ⅱ, male 21, female 24） did not. The average follow-up period for group Ⅰ and Ⅱ were 25 and 30 months, respectively. During the follow-up period, the recurrent rate and recurrence of extracranial metastatic meningioma were recorded. Results The patients in group I had significantly higher intraoperative blood loss than those in group Ⅱ, a fewer patients were transfused with banked blood（7.9 % in group Ⅰ vs 24.4 % in group Ⅱ, P 〈 0.001）. The recurrent rate of the patients undergone Simpson grade I resection were 7.6 % and 11.8 % in 2 groups, respectively（P = 0.75）. No extracranial metastases case was found in both groups. Conclusion There is no increasing risk of recurrence or metastasis of meningioma in the patients transfused with intraoperatively salvaged blood during the follow-up study.
出处
《生物医学工程与临床》
CAS
2009年第3期228-231,共4页
Biomedical Engineering and Clinical Medicine
关键词
输血
自体
脑膜瘤
肿瘤转移
blood transfusion, autologous
meningioma
neoplasm metastases
