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犬子宫积脓病的诊断及动物模型的建立 被引量:2

Diagnoses of Canine Pyometra and the Animal Model Establ:sbment
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摘要 为研究犬子宫积脓的病因,对2007年7月~2008年10月期间,沈阳地区的33例犬子宫积脓病例进行了病史调查及临床检查、血细胞检查、雌孕激素测定和子宫内容物细菌培养,采用注射雌孕激素和丝线埋置的方法建立动物模型。结果表明:发病年龄平均7.5岁,6岁以上患病占88%,患病犬中有24.2%以上注射过激素,白细胞(WBC)的平均值为45.7×10^9个·L^-1,孕酮的平均值为(0.2263±0.05744)ng·mL^-1,雌二醇的平均量为(2.7214±0.03486)pg·m^L-1,大肠肝菌(E.coli)为61.9%,是主要感染细菌,动物模型证明孕酮与本病关系密切,雌激素和细菌感染会更快产生病变。 For the research fo the pathogenisis of canine Pyometra, in the period from July 2007 to October 2008 in Shenyang, 33 cases of Canine Pyometra were investigated for the case history examination, clinical examination, blood eytoscopy, determination of the E2 and P4, bacterial culture of the utero-eontent. The average age of onset was 7.5 year,the percent of the bitch with disease above 6 years was 88%,the percent of the dogs with disease which injected the hormone was above 24%, the general average of WBC was 45.7×109cells·L^-1,the general average of P4 was (0.2127±0.0731)ng·mL^-1, the general average of the E2 was (2.7312±0.4751)pg·mL^-1,the percent of E.coli was 61.9% and it was the main bacterial infection. Animal model proved that the disease was closely related with the P4,E2 and bacterial infection would accelerate the disease.
出处 《沈阳农业大学学报》 CAS CSCD 北大核心 2009年第2期230-233,共4页 Journal of Shenyang Agricultural University
关键词 子宫积脓 血细胞 激素 细菌 动物模型 canine pyometra blood hormone bacteria animal model
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参考文献11

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