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高血压与胰岛素抵抗及心功能关系的研究 被引量:1

Relationship of Hypertension,Insulin Resistance and Heart Function
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摘要 目的研究高血压与胰岛素水平及心脏功能的关系。方法筛选52例新入院患者,正常血压患者27例,高血压患者25例,在未用药前,测24 h动态血压,空腹及餐后2 h血糖及心脏彩超测量左心大小、射血分数。比较研究高血压组病人与正常血压组病人的血糖、胰岛素水平及左心室大小、射血分数。结果高血压组患者的血糖、胰岛素水平明显高于正常血压组;高血压组的左心室明显大于正常血压组,射血分数无明显差异。结论胰岛素抵抗可能参与了高血压的发病过程,高血压与糖尿病可能有共同的发病机制。高血压与胰岛素抵抗可能使心脏的功能发生变化,左心室扩大。 Objective To detect the hypertension and insulin resistance on the left ventricle and heart function. Methods 52 patients were enrolled in the research, 27 of whom were non-hypertensive and the others were hypertensive. Without being administrated medicine, 24 hours ambulatory blood pressure was monitored, fasting and 2 hours after drinking 75g glucose, the blood glucose was tested. All the patients were submitted to electrocardiogram, diameter of left ventricle and ejection fraction were detected. The differences of the level blood glucose, blood insulin, left ventricle and EF between the hypertension group and the non - hypertension group were compared. Results The blood glucose, blood insulin, diameter of left ventricle of the patients with hypertension were significantly higher than the patients without hypertension. Conclusion Insulin resistance may be involved in the mechanism of hypertension. Hypertension and diabetes mellitus maybe share the common starting line. Hypertension and insulin resistance may cause the dilation of the left ventricle.
出处 《河南职工医学院学报》 2009年第2期122-124,共3页 Journal of Henan Medical College For Staff and Workers
关键词 高血压 胰岛素抵抗 血糖 射血分数 左室内径 hypertension insulin resistance blood glucose ejection fraction diameter of left ventricle
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