奥美拉唑治疗非静脉曲张性上消化道出血的疗效观察被引量：9

Clinical Observation on Therapeutic Effect of Omeprazole on Nonvariceal Upper Gastrointestinal Bleeding

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摘要目的:观察奥美拉唑治疗非静脉曲张性上消化道出血的疗效。方法:将246例非静脉曲张性上消化道出血患者作为研究对象,随机分为3组,分别为奥美拉唑静脉滴注组、奥美拉唑80 mg泵入组、奥美拉唑160 mg泵入组,各组患者数均为82例,然后比较各组治疗方法的临床疗效。结果:不同给药治疗方法疗效有显著性差别(P<0.05)。结论:奥美拉唑持续静脉泵入治疗非静脉曲张性上消化道出血效果好于奥美拉唑分次静脉滴注,且大剂量奥美拉唑持续泵入治疗能够达到更好的止血效果。 OBJECTIVE：To observe the therapeutic effect of omeprazole in treating nonvariceal upper gastrointestinal bleeding. METHODS： 246 patients of nonvariceal upper gastrointestinal bleeding were divided into 3 groups at random： parenteral infusion of omeprazole, pumping of 80 mg omeprazole; pumping of 160 mg omeprazole. Then three groups of 82 patients were made a comparison on the therapeutic effect after different therapies. RESULTS：The therapeutic effects after different therapies have significant differences （ P 〈 0.05）. CONCLUSION：The therapeutic effect of pumping of omeprazole is better than parenteral infusion of omeprazole in treating nonvariceal upper gastrointestinal bleeding. And constant pumping of large dose of omeprazole can arrest bleeding more effectively.

作者乔进朋鲁力锋王晓燕张莉王艳

机构地区北京丰台医院消化内科

出处《中国医院用药评价与分析》 2009年第4期311-312,共2页 Evaluation and Analysis of Drug-use in Hospitals of China

关键词奥美拉唑非静脉曲张性上消化道出血疗效 Omeprazole Nonvariceal upper gastrointestinal bleeding Therapeutic effect

分类号 R975.2 [医药卫生—药品]

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参考文献4

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二级参考文献14

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