摘要
目的:探讨老年高血压病患者中医辨证分型及其与心率变异性(heart rate variability,HRV)的关系。方法:选择符合诊断标准的老年高血压病患者90例,按中医临床辨证分为肝火亢盛型、痰湿壅盛型、阴虚阳亢型、阴阳两虚型4组,20例正常健康人作为对照组,采用24h动态心电图和心率变异性检测技术,将24h窦性心搏进行HRV时域分析和频域分析,对正常人及不同证型分组的老年高血压病患者进行比较研究。结果:老年高血压4种证型HRV时域分析指标均低于正常对照组,肝火亢盛组SDANN,痰湿壅盛组SDANN、RMSSD,阴虚阳亢组SDNN、SDANN、RMSSD、PNN50,以及阴阳两虚组SDNN、SDANN、RMSSD、PNN50与对照组相比有显著性差异(P(0.05)。频域分析结果表明各证型LF、HF均低于正常对照组,且有统计学意义(P(0.05)。各证型组间比较显示,心率变异依次为正常对照组(肝火亢盛组(痰湿壅盛组(阴虚阳亢组(阴阳两虚组。结论:中医不同证型老年高血压与心率变异之间存在一定关系。
Objective： To explore the correlation of TCM syndrome differentiation of elderly patients with hypertension and heart rate variability（HRV）. Methods ：90 cases of elderly patients with hypertension were divided into four syndrome groups according to diagnostic criteria; liverfire hyperactivity syndrome, abundant phlegm -dampness syndrome, yin- deficiency and excessive yang syndrome,）,inyang deficiency syndrome, and 20 healthy people were observed as control group. HRV related indexes were detected with 24h Holter monitoring electrocardiogram. Results ： Compared with the con- trol group, HRV time domain analysis of the four syndromes of the old hypertension decreased, SDANN of liver - fire hy- peractivity syndrome; SDANN, RMSSD of abundant phlegm - dampness syndrome; SDNN, SDANN, RMSSD, PNN50 of ）,in - deficiency and excessive yang syndrome and yin - yang deficiency syndrome had significant difference （ P 〈 0.05 ）. The results of frequency domain analysis indicated that LF, HF of four syndrome groups decreased than that of the control （P 〈 0.05 ）. The comparison among the four syndrome showed ; liver - kidney yin deficiency 〉 abundant phlegm - dampness syndrome 〉 yin - deficiency and excessive yang 〉 yin - yang deficiency, and there were significant difference between dif- ferent syndromes（P 〈 0.05 ）. Conclusion：There were some relations between different syndrome of elderly patients with hypertension mad some HRV indexes can be used for the reference of Chinese medical syndrome differentiation.
出处
《中华中医药学刊》
CAS
2009年第5期1115-1117,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
老年高血压病
心率变异性
自主神经系统
中医辨证分型
elderly patients with hypertension
heart rate variability （HRV）
autonomic nervous system
TCM syndrome differentiation
