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正交设计法对二妙胶囊醇提取工艺的研究

Studies on Alcohol Extraction Process in ErMiao Capsules by Orthogonal Design
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摘要 目的:优选二妙胶囊中黄柏最佳提取工艺。方法:采用正交设计L9(34)法,以总浸膏量和盐酸小檗碱的含量为指标,综合评分考察。结果:最佳提取工艺为10倍量的70%乙醇回流提取3次,每次1.5h。结论:优选得到的工艺合理可行。 Objective: To optimize the best extraction process of cortex phellodendri in ErMiao capsules. Methods : orthogonal design L9 ( 3^4 ) was used to study the best extraction condition with the content of the synthesized evaluation of total extraction and berberine. Results: The optimum extraction condition was as follow: coarse powder,70 percent ethanol, refusing and extracting for 3 times,total 1.5 hours,10 folds of 70% ethanol. Conclusion: The optimum technology condition is reasonable and practicable for extraction.
出处 《中华中医药学刊》 CAS 2009年第5期1087-1088,共2页 Chinese Archives of Traditional Chinese Medicine
关键词 二妙胶囊 盐酸小檗碱 正交实验 Ermiao capsules berberine orthogonal design
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