摘要
目的 研究保留迷走神经的食管贲门癌切除术对术后生活质量的影响.方法 对39例无外侵的早中期食管贲门癌患者施行根治性切除中迷走神经保留术,并随机选取39例未保留迷走神经的常规手术作对照组.术后通过胃排空时间、血胃泌素含量测定、近期营养学计算来研究保留迷走神经的食管贲门癌切除术后胃肠消化功能.结果 保留组胃排空时间T1/2均数值20.3±8.9分和血胃泌素水平均数值34.2±18.5mg/L与对照组胃排空时间T1/2均数值35.7 ±5.8分和血胃泌素水平均数值56.5±21.6ng/L相比有显著差别,分别为P<0.01和P<0.05).术后近期营养学计算显示,保留组在术后短期内摄入量及营养状况达到正常,与对照组相比差异显著(P<0.05).结论 在早中期无周围外侵的食管贲门癌患者切除中保留迷走神经对于防止病人术后消化功能紊乱,提高生活质量有着重要的临床意义.
PURPOSEStudy and evaluate the clinical value of preserving vagal trunks in the surgical treatment of early esophageal cancer and cardia carcinoma. METHODS From December 1994 to May 1996, we preserved vagal trunks in the surgical treatment of 39 patients with early esophageal and cardia carcinoma. At the same time 39 randomly selected patients as control proup treated by routine resection. After the operation, we studied the patient's digestive function to determine gastric emptying time and blood gastrin assay and recent results of nutritional intake. RESULTS Gastric emptying time and blood gastrin revealed a mean value of 20. 3 ± 8. 9 min and 34. 2 ng/L for the preserved group, which were statistically different from those of 35. 7±15. 8 min and 56. 5±21. 6 ng/ L. in the control group(P1<0. 01. P2<0. 05). The results of postoperative nutrition assay show: the intake and nutritional condition reached normal levels after a short time in the preserving group were statistically different from the control group (P<0. 05) .CONCLUSION We consider that preserving vagal trunks in the surgical treatment of early esophageal and cardia carcinoma is of clinical significance in preventing postoperative digestive dysfunction and improving quality of life.
出处
《中国癌症杂志》
CAS
CSCD
1998年第1期12-14,共3页
China Oncology
关键词
食管肿瘤
贲门癌
迷走神经保留术
生活质量
Tumor Esophageal and cardia cancer Preserving vagal trunks Quality of life
