摘要
目的:通过测量原发性高血压病不同中医证型患者的颈总动脉内中膜厚度及斑块积分。探讨高血压病不同中医证型与这些指标的相关性,为高血压病中医辨证客观化的研究提供依据。方法:60例原发性高血压病患者按中医辨证分型分为阴阳两虚证(10例),痰湿壅盛证(14例),阴虚阳亢证(28例),肝火亢盛证(8例)及30例正常血压对照组,应用高分辨力超声对颈总后壁的内膜内表面到中膜外表面的距离(IMT)测量,同时注意观察颈动脉粥样硬化斑块的位置、数量及斑块性质等。结果:高血压病各证型与正常对照组的IMT值比较差异有显著性意义(P均<0.05),高血压病组各证型之间IMT比较,差别也非常显著,高血压病各证型之间IMT值比较,阴阳两虚、痰湿壅盛>阴虚阳亢>肝火亢盛。颈动脉粥样硬化斑块积分比较,差别也非常显著,高血压病各证型之间斑块积分值比较,痰湿壅盛>阴阳两虚>阴虚阳亢、肝火亢盛。结论:颈动脉IMT,颈动脉粥样硬化斑块积分法可作为高血压病中医分型的辨证的参考指标。
Objective：To investigate the changes of carotid intima-media thickness（IMT） and carotid artery plaque score, and to analyse these changes in different patients with essential hypertension by Traditional Chinese Medical （TCM）classification for providing differentiating zheng impersonal guideline of essential hypertension in TCM. Methods：60 patients with essential hypertension were divided into four types： yin yang concurrent deficiency type （ 10 cases）, stagnation of phlegm-dampness type （ 14 cases）, yin deficiency yang hyperactivities type （28 cases ）, liver fire exuberance type （8cases）, and 30 cases with normal blood pressure were used as control group. High resolution ultrasound was used to measure carotid artery plaque score, and IMT of carotid artery. And their relationship was analyzed for the PEMS 3.1 statistical package. Results ： Compared with the normal control, carotid artery plaque score and the IMT in different type of essential hypertension with TCM classification had significant difference （P 〈 0.05 ）. In contrast with the IMT value of different types in the essential hypretension, the value level from high to low were respectively ： Yin yang concurrent deficiency type , stagnation of phlegm-dampness type 〉 yin deficiency yang hyperactivities type 〉 liver fire exuberancc type, while in which carotid artery plaque score value level seriatim were opposite from high to low. Stagnation of phlegm-dampness type 〉 yin yang concurrent deficiency type 〉 yin deficiency yang hyperactivities type, liver fire exuberance type. Conclusion ： the value of IMT and carotid artery plaque score may be to used as the reference index of TCM classification of the essential hypertension.
出处
《辽宁中医杂志》
CAS
北大核心
2009年第5期689-691,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
广西卫生厅资助项目(Z2006092)
关键词
原发性高血压病
中医分型
颈动脉内中膜厚度
斑块积分
Essential hypertension
TCM classification
Carotid intima-media thickness
Carotid artery plaque score
