摘要
目的总结经单鼻孔蝶窦入路内镜辅助显微手术治疗垂体腺瘤的初步体会,探讨其技术优势、评价其疗效。方法回顾性分析2000～2006年间经单鼻孔蝶窦入路内镜辅助显微手术治疗的40例垂体腺瘤的临床资料。结果本组40例垂体腺瘤患者,36例全切除,4例次全切除。患者术后症状均改善,视野缺损(偏盲)在术后1周内基本恢复,视力减退、泌乳等症状有明显改善。术后并发症为暂时性尿崩症15例,多于术后2周内停止;脑脊液漏2例,经保守治疗痊愈;无颅内感染、无鼻中隔穿孔等并发症;1例于术后3年复发,再次经单鼻孔蝶窦显微手术次全切除(肿瘤已侵袭海绵窦),术后辅以放疗。结论内镜辅助的直接经单鼻孔蝶窦显微手术是治疗垂体腺瘤的一种安全、微创、有效的方法。
Objective With summing up our primary clinical experience of the endoscope assisted endonasal transsphenoidal microsurgery for pituitary adenoma, to explore its advantages and evaluate its effect. Methods The clinical data of 40 cases with pituitary adenoma treated by endoscope assisted transsphenoidal approach was studied retrospectively. Results Of the 40 patients with pituitary adenoma were totally removed in 36 cases, and subtotally removed in 4 cases. Symptoms of the patients were all improved. Preoperative visual field defects was recovered in one week. Dminished acuity and lactation were improved. Postoperative temporary diabetes insipidus occurred in 15 patients and recovered 2 weeks after surgery. Cerebrospinal fluid leakage occurred in two patients and was cured with conservative treatment. No occurrence of intracranial infection and perforation of nasal septum was observed. Pituitary adenoma recurred in one patient 3 years after surgery and was subtotally removed with endoscope assisted endonasal transsphenoidal microsurgery again（ Cavernous Sinus was invaded）. Conclusions The endoscope assisted endonasal transsphenoidal microsurgery for pituitary ade- noma is a safe, minimal invasive and effective technique.
出处
《国际神经病学神经外科学杂志》
2009年第2期125-127,共3页
Journal of International Neurology and Neurosurgery
关键词
垂体腺瘤
经鼻蝶入路
内镜
显微手术
Pituitary adenoma
Endonasal transsphenoidal approach
Endoscope
Microsurgery
