摘要
【目的】观察加味白术汤治疗虚秘型便秘的临床疗效。【方法】采用随机分组对照试验方法,将86例虚秘型便秘患者随机分为治疗组(58例)和对照组(28例),分别以加味白术汤汤剂(由白术、熟地、菟丝子、当归、肉苁蓉、牛蒡子、桔梗、槟榔等中药组成)及酚酞片治疗,疗程4周,观察停药2周后的临床效果和排便间隔时间的变化。【结果】(1)治疗组服药1d后即出现不同程度排便的有30例(占51.72%),对照组有16例(占57.14%),两组比较差异无显著性意义(P>0.05)。(2)停药2周后,治疗组和对照组的总有效率分别为89.65%和46.43%,两组比较治疗组疗效优于对照组(P<0.01)。(3)治疗后2组患者的排便间隔时间均有显著缩短(与治疗前比较,P<0.01);且治疗组在停药2周后的排便间隔时间较对照组显著缩短(P<0.01)。【结论】加味白术汤治疗虚秘型便秘的近期疗效与酚酞片相当,而远期疗效则优于酚酞片。
Objective To observe the effect of modified Baizhu Decoction （MBD） on deficiency constipation. Methods Eighty-six patients with deficiency constipation were randomized into treatment group （N = 58 ） and control group （N = 28 ） , which were given MBD and phenolphthalein tablets respectively for 4 weeks. The effectstarting time, therapeutic effect after suspension for 2 weeks, and interval of defecation were observed. Results （1） One day after administration, different degrees of defecation occurred in 30 （51.72%） patients of the treatment group and in 16 （57.14%） of the control group, the difference being insignificant （P 〉0. 05）. （2） After suspension for 2 weeks, the total effective rate was 89.65% in the treatment group and 46.43% in the control group, the difference being significant between the two groups （ P 〈 0. 01 ）. （3） The interval of defecation was shortened in the two groups after treatment （P 〈 0.01 compared with that before treatment）, and the shortening of defecation interval was obvious in the treatment group （ P 〈 0. 01 compared with that in the control group）. Conclusion The short-term effect of modified Baizhu Decoction on deficiency constipation is similar to that of phenolphthalein tablets, but the long-term effect is better.
出处
《广州中医药大学学报》
CAS
2009年第3期228-230,共3页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
虚秘型便秘/中药疗法
加味白术汤/治疗应用
DEFICIENCY CONSTIPATION/TCD therapy
MODIFIED BAIZHU DECOCTION/therapeutic use
