摘要
目的：通过对血清与脑脊液髓鞘碱性蛋白（MBP）检测比较，探讨其临床价值。方法：采用简易的MBP酶联无疫吸附定量测定（ELISA）法检测。结果：对照组血清、脑脊液中MBP含量分别为0．99±0.48μg／L；1．59±0．51μg／L．急性颅脑损伤后不同时间（1，3，5，7d）M脊液中MBP含量分别为8.79±1．89μg／L；719±1．87μg／L，5．18±1．19μg／L；3．19±1，77μg/L．血清中MBP含量分别为1．78±0．78μg／L；3．51±0．94μg／L；3．98±1．07μg／L；289±1．22μg／L。检测结果均与对照组有非常显著性差异（P＜0．01；P＜0．05）。结论：急性颅脑损伤早期脑脊波中MBP含量较血清中升高非常显著，对判断伤情及预后有指导意义。
Objective To discuss the clinical value by comparison of assays for myelin basic protein in serum andCSF. Methods Simplified enzyme-linked immunoadsorbent assay (ELISA) for myelin basic protein (MBP). Re-sults Control group MBP concentrations in the serum and CSF were 0. 99±0. 48 pg/L and 1. 59±0. 51 μg/L.MBP concentrations in serum and CSF were statistically significant differences between control groups and pa-tients with acute brain injury (P<0.01 or P<0. 05). Conclusion It was shown that MBP level was related withthe severity and prognosis of case.
出处
《陕西医学检验》
1998年第1期4-5,共2页
Shaanxi Journal of Medical Laboratory Sciences
