摘要
为了降低创伤感染病原菌的耐药性，做到合理用药，充分发挥抗生素在抗感染治疗中的最佳疗效。对我院近期病原菌的耐药性及抗生素的使用情况进行了调查分析。共统计送检标本７１０例次，分离培养出病原菌１５种５０７株，阳性检出率为７１．４％；共调查住院病例３８８份，使用抗生素３０１人，使用率为７７．６％。结果表明，内源性的“正常菌群”和／或来自周围环境中的非致病菌已成为目前创伤感染的主要致病菌。这与临床抗生素应用中所存在的使用率高、剂量大、疗程长、预防用药多、使用指征不明确、无目的联合等不合理现象有关。
n investigation was made on the shortterm drug resistance of pathogenic bacteria (DRPB) and the use conditions of antibiotics in our hospital as to reduce DRPB and obtain the best therapeutic effects of antibiotics in antiinfective treatment. From 710 examined specimens counted, 15 species (507 strains) of pathogenic bacteria were separated and cultured with a positive detectable rate of 71.4 %; and of 388 inpatients investigated, 301 were users of antibiotics with a use rate of 77.6 %. The results suggested that endogenous “normal flora” and /or nonpathogenic bacteria from the surroundings have become todays main pathogenic bacteria in traumatic infections, which is related to the irrational phenomena in clinical application of antibiotics, such as high use rate, great dosage, long therapeutic course, many preventive drugs used, indefinite indications, nonpurposive combination, and so on.
出处
《中医正骨》
1998年第2期8-9,11,共3页
The Journal of Traditional Chinese Orthopedics and Traumatology
关键词
创伤感染
病原菌
抗生素
治疗
infection, traumatic/seizure pathogenic bacteria/pathogenicity antibiotics/usage and dosage investigation
