摘要
为了研究白癜风的细胞免疫变化，我们应用ＥＬＩＳＡ技术检测了４１例非节段型白癜风病人及３０例正常人血清白介素２（ＩＬ－２）和肿瘤坏死因子（ＴＮＦα）的水平，同时检测了血清可溶性白介素２受体（ｓＩＬ－２Ｒ）的水平。结果显示白癜风病人的血清ＩＬ－２水平明显下降，ｓＩＬ－２Ｒ和ＴＮＦα水平明显增高。研究表明非节段型白癜风病人存在细胞免疫缺陷，提示免疫机制在白癜风发病中可能起作用。
The concentrations of interleukin 2(IL-2), soluble interleukin-2 receptor(sIL-2R) and tumor necrosis factor (TNFα)were measured in the sera of patients with non-segmental vitiligo (n=41)and in healthy controls (n=30) by and ELISA technique in order to investigate the changes in cellular immunity in vitiligo. The results showed that serum IL-2 levels were significantly decreased and serum levels of sIL-2R and TNFα were significantly elevated in vitiligo group compare with normal controls. These results indicate that deficiencies in cellular immunity may be present in non-segmental vitiligo patients, and suggest that immune mechanisms may be involved in the pathogenesis of vitiligo.
出处
《皮肤病与性病》
1998年第1期1-3,共3页
Dermatology and Venereology
