摘要
目的研究原发性干燥综合征（pSS）合并恶性肿瘤的特点以及高危因素。方法回顾性分析29例pSS合并恶性肿瘤患者的临床特点。结果pSS合并恶性肿瘤（29例）占所有住院pSS患者（1320例）的2．2％。在29例pSS合并恶性肿瘤患者中淋巴瘤8例（非霍奇金淋巴瘤7例，不明分型1例），乳腺癌4例，骨髓瘤、胸腺瘤、肺癌、胃腺癌、结肠癌、舌鳞癌各2例，肝癌、宫颈癌、肾癌、甲状腺癌、腮腺黏液表皮样癌各1例。结论pSS合并恶性肿瘤中以淋巴瘤最多见；其主要类型为B细胞非霍奇金淋巴瘤。
Objective To investigate the clinical features and risk factors of primary Sjogren＇s syndrome （pSS） patients with malignancies. Methods The clinical features of＂ 29 pSS patients with malignancies from January 1985 to March 2008 were retrospectively analyzed. Results The ratio of pSS with malignancies to all hospitalized pSS patients from January 1985 to March 2008 was 2.2%. In these patients, 8 were lymphoma, 4 were breast cancers, 2 were myeloma, 2 were thymoma, 2 were lung cancer, 2 were gastric carcinoma, 2 were hepatoma, 2 were colon carcinoma and 2 were tongue cancer. Uterine cervix cancer, renal carcinoma, thyroid carcinoma and carcinoma of parotid gland each were fund in this series of patients. Conclusion The most common malignancy in pSS is lymphoma and the major of pathological type is B cell non-Hodgkin＇s lymphoma.
出处
《中华风湿病学杂志》
CAS
CSCD
北大核心
2009年第5期336-338,共3页
Chinese Journal of Rheumatology
关键词
干燥综合征
淋巴瘤
非霍奇金
肿瘤
Sjogren＇s syndrome
Lymphoma, non-Hodgkin＇s
Neoplasms
