摘要
目的探讨老年急性白血病患者院内感染及治疗情况，以期提高治疗水平。方法回顾分析３８例老年急性白血病患者的院内感染发生率、感染部位、危险因素和治疗情况等，并与同期１５７例非老年患者进行比较。结果老年组发生院内感染３０例（７８．９％），高于同期非老年组（９２例，５９．０％）。感染部位以呼吸系统多见（２０例，６２．５％）。危险因素为白细胞减少和化疗。单纯抗生素治疗有效率３１．３％，抗生素加辅助治疗有效率６６．７％，二者相比差异有显著性（Ｐ＜０．０５）。治疗总有效率为５２．５％。结论老年急性白血病患者院内感染发生率高于同期非老年组。抗生素加辅助治疗优于单纯抗生素治疗。控制感染与骨髓缓解有关。
Objective To improve the treatment of the hospital infection of the elderly patients with acute leukemia. Methods The data of the hospital infection and treatment of 38 elderly acute leukemic patients were reviewed, including the incidence of nosocomial infection, the most commonly infected site, the risk factors and the overall response rate. Results The incidence of nosocomial infection was 789%. The most commonly infected site was respiratory system (625%). The factors of high risk included low WBC (867%) and chemotherapy (767%). The response rate with antibiotics alone and antibiotics combined with supportive therapy was 313% and 667% respectively (P<005). The overall response rate was 525%. Conclusions The incidence of nosocominal infection of elderly acute leukemic patients was higher than nonelderly group in the same period. The combination of antibiotics with supportive therapy was better than antibiotics alone. Control of infection is related to acute leukemic remission.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1998年第1期29-31,共3页
Chinese Journal of Geriatrics
关键词
急性
白血病
医院感染
药物疗法
老年人
Leukemia, lymphocytic, acute Leukemia, nonlymphocytic, acute Cross infection
