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慢性乙型肝炎患者sIL-2R水平、mIL-2R表达及T细胞亚群的检测及意义 被引量:3

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摘要 目的:探讨慢性乙型肝炎病人血清可溶性白细胞介素—2受体(sIL—2R)水平、淋巴细胞膜白细胞介素—2受体(mIL—2R)表达及T细胞亚群的变化及意义。方法:分别采用双抗体夹心ELISA法和碱性磷酸酶抗碱性磷酸酶(APAAP)法检测了108例慢性乙型肝炎病人血清sIL—2R、mIL-2R表达及T细胞亚群(CD4、CD8)的变化,并与66例同期健康人进行了对照。结果:慢性乙型肝炎病人sIL—2R、CD8明显增高,mIL—2R、CD4、CD4/CD8明显降低,与对照组比较差异有极显著性(P<0.001),慢性活动性肝炎(CAH)较慢性迁延性肝炎(CPH)变化更明显(P<0.001)。结论:sIL—2R水平、mIL—2R表达和T淋巴细胞亚群的变化与慢性乙型肝炎病人病情及预后有关。
出处 《河北医学》 CAS 1998年第1期28-30,共3页 Hebei Medicine
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二级参考文献3

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同被引文献15

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