摘要
目的:报道1例椎管内髓外硬膜下支气管源性囊肿,结合文献探讨其临床病理学特征及诊断、鉴别诊断要点。方法:对1例椎管内髓外硬膜下支气管源性囊肿进行临床病理分析及免疫组化观察。结果:髓外硬膜下支气管源性囊肿临床症状可表现为囊肿部位的神经根痛,以后发展为脊髓压迫症;镜下可见纤维囊壁内衬覆复层上皮细胞或假复层纤毛柱状上皮,免疫组化染色囊壁内衬覆上皮细胞CK、EMA阳性,而GFAP、NSE阴性,PAS染色在复层上皮细胞或假复层柱状上皮细胞的游离缘上见到纤毛。结论:椎管内髓外硬膜下支气管源性囊肿是一种罕见病变,其诊断和鉴别诊断主要依靠病理组织学和免疫组化检测,其治疗多采取手术完整切除,预后较好。
Objective： To report one case of cervical intradural extramedullary bronchogenic cyst and to discuss its clinical and histopathologic features, diagnosis and differentiation diagnosis. Methods：Histopathology and immunohistoehemistry observation were performed. Results：The chnical symptom of intradural extramedullary bronchogenic cyst could be radiculalgia and later could develop into spinal compression. In immunohistochemistry, the tumor ceils were positive for CK, EMA, and negative for GFAP, NSE. The cilia on the free edge of laminated epithelium cell and pseudostratified columnar epithelium cell could be shown by PAS staining. Conclusion：Extramedullary subdura bronchogenic cyst is a rare lesion. Its diagnosis and differentiation diagnosis mostly relied on histopathology and immunohistochemistry. Definitive treatment requires surgical excision.
出处
《现代肿瘤医学》
CAS
2009年第5期834-836,共3页
Journal of Modern Oncology
关键词
髓外硬膜下
支气管源性囊肿
组织病理学
免疫组化
intradural extramedullary
bronchogenic cyst
histopathology
immunohistochemistry
