摘要
目的观察人胎盘脂多糖辅助治疗儿童支气管哮喘的临床疗效。方法将我院91例支气管哮喘患儿随机分成2组,治疗组46例,采用综合疗法,发作期应用沙丁胺醇、普米克令舒、氨茶碱治疗,缓解期肌内注射人胎盘脂多糖、气雾吸入倍氯米松;对照组45例,发作期用沙丁胺醇、普米克令舒、氨茶碱治疗,缓解期气雾吸入倍氯米松。结果治疗2周后治疗组、对照组对改善喘息、咳嗽症状比较,差异有显著性意义(P<0.05)。随访1年,治疗组复发率与对照组比较,差异有显著性意义(P<0.05)。结论人胎盘脂多糖辅助治疗支气管哮喘疗效确切,复发率低,值得临床推广应用。
Objective To observe the clinical effect of human placenta lipopolysaccharides as auxiliary treatment of children bronchial asthma. Methods 91 children with bronchial asthma were selected in our hospital and randomly divided into two groups. 46 cases were in the treated group; 45 cases in the control group. The treated group received the composite treatment. During the attack period, Salbutamol, Pulmincort, Aminophylline were used to treat the treated group. Later Human placenta lipopolysaccharides were injected and gas spray inspiration of Beclomethasone was applied during the remission period. On the other hand, Salbutamol, Pulmincort, Aminophylline were used to treat the control group during the attack period. Then only the gas spray inspiration of Beclomethasone was applied in the remission period. Results Two weeks later, the effect is more obvious in the treated group than the control group in terms of improving symptoms such as respite, cough,with a notable difference of P〈0.05. One year later, there.is a notable difference of P〈0.05 in terms of the recurrence rate between the treated group and the control group. Conclusion Human placenta lipopolysaccharides had some effect in treating bronchial asthma and the recurrence rate was low when it was used. It is worth promoting the clinical application of human placenta lipopolysaccharides in treating bronchial asthma.
出处
《中国医药指南》
2009年第7期17-18,共2页
Guide of China Medicine
关键词
儿童
支气管哮喘
人胎盘脂多糖
Children
Bronchial asthma
Human placenta lipopolysaccharides
