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脐血瘦素与新生儿免疫关系的探讨 被引量：4

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摘要 目的:探讨脐血瘦素浓度与新生儿免疫的关系。方法:选择2006年1～9月青岛海慈医疗集团产科足月单胎分娩产妇93例,采用速率散射法免疫浊度测定系统测定脐血IgG、IgA、IgM含量,放射免疫法检测脐血瘦素水平,采用单抗桥联酶标法测定T细胞亚群。结果:①足月新生儿阴道分娩脐血瘦素浓度(15.31±5.43)ng/ml,新生儿性别间差异无统计学意义。②新生儿脐血瘦素浓度与新生儿免疫功能有相关性,脐血瘦素浓度与体液免疫IgG有统计学相关性(r=0.256,P<0.05),而与IgA、IgM无统计学相关性(r=0.187,P>0.05;r=0.149,P>0.05);脐血瘦素质量浓度与CD4淋巴细胞百分率有统计学相关性(r=0.263,P<0.05),CD8淋巴细胞百分率有明显统计学相关性(r=0.362,P<0.01)。结论:脐血瘦素与新生儿免疫功能有相关性,瘦素参与胎儿免疫功能和生长发育的调节。
作者 解梅琳 刘爱红
机构地区 山东省青岛市海慈医疗集团产科
出处 《中国妇幼保健》 CAS 北大核心 2009年第12期1636-1637,共2页 Maternal and Child Health Care of China
关键词 瘦素 免疫功能 体重指数
分类号 R722 [医药卫生—儿科]
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共引文献66

同被引文献28

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引证文献4

二级引证文献47

中国妇幼保健
2009年 第12期

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