摘要
目的探讨可消除司帕沙星片抑菌活性的微生物限度检查方法。方法采用薄膜过滤法和硫酸锰中和法联合测定,根据供试品污染试验菌的回收率来选择适宜的检验方法。结果5种实验菌株回收率均大于70%,通过回收率测定确定了加入硫酸锰溶液的量。结论本法与普通的薄膜过滤法相比,更能消除司帕沙星片的抑菌活性,方法更可行、可靠。
Objective To explore a method for eliminating the antibacterial action of sparfloxacin tablet in microbial limit test. Methods Joint determination with membrane filtration plus manganous sulfate solution were used and the recovery was calculated. Results The average recoveries were all over 70%, the amotmt of manganous sulfate solution had been determined. Conclusion Joint determination is convenient and reliable and it is superior to that of membrane filtration method .
出处
《中国热带医学》
CAS
2009年第5期932-933,共2页
China Tropical Medicine
关键词
薄膜过滤法
中和法
司帕沙星片
硫酸锰溶液
微生物限度
Membrane filtration
Neutralization
Sparfloxacin Tablet
Manganous sulfate solution
Microbial limit test
