摘要
目的观察脑梗死疾病中超敏C-反应蛋白(hs-CRP)与血脂的关系。方法测定45例脑梗死患者和50例健康人血清中hs-CRP和血脂〔三酰甘油(TG)、胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)〕水平。结果脑梗死患者血清中hs-CRP、TC、TG、LDL-C和TG/HDL-C均显著高于健康对照组,且与TG呈正相关,与HDL-C呈负相关关系;应用ROC曲线分析hs-CRP、TC、TG、LDL-C、TG/HDL-C在脑梗死诊断中的价值,发现hs-CRP的ROC曲线下面积为0.905,大于后四者。结论hs-CRP与血脂联合分析,可预测脑梗死疾病的发展及判断疾病的预后。
Objective To investigate the relationship between high-sensitivity C-reactive protein （hs-CRP） and blood lipids in cerebral infarction. Methods Serum levels of hs-CRP and blood lipids （TG,TC, HDL-C, LDL-C and TG/HDL-C） were measured in 45 patients with cerebral infarction （cerebral infarction group） and 50 healthy people （healthy control group）. Results The patients with cerebral infarction had a significant higher serum levels of hs- CRP,TC,TG, LDL-C and TG/HDL-C compared with the control group. Furthermore, the levels of hs-CRP were positively correlated with TG, and negatively correlated with HDL-C. By analyzing the value of hs-CRP, TC, TG, LDL-C,TG/HDL-C in diagnosis of cerebral infarction by ROC curve, we found that the area under ROC curve of hs- CRP （0. 905） was bigger than that of TC,TG,LDL-C or TG/HDL-C. Conclusion The measurement hs-CRP and blood lipids contributes to prognosis evaluation and pathogenetic condition minitoring of cerebral infarction.
出处
《检验医学与临床》
CAS
2009年第8期568-569,共2页
Laboratory Medicine and Clinic
