摘要
目的测定７５例糖尿病患者血浆阿片肽的改变。方法用放射免疫法测定β内啡肽、亮啡肽及强啡肽Ａ１１３。结果３种阿片肽均随病程的延长而下降，尤以强啡肽Ａ１１３为明显。血糖较高者及并发神经病变和高血压者降低更明显。
Objective Estimating 3 plasma opioid peptides in 75 cases of diabetes. Methods Plasma β endorphin, leu enkephalin and dynorphin A 1 13 were estimated by RIA. Results Three opioid peptides decreased with the course of diabetes and dynorphin A 1 13 was the most obvious of them. The higher the blood glucose level and the incidence of neuropathy and hypertension, the lower will be the opioid peptides. Conclusion Dynorphin A 1 13 shows the most obvious decrease in relation to course and complications of diabetes.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1998年第1期22-24,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
Β-内啡肽
亮啡肽
强啡肽A1-13
糖尿病
β Endorphin
Leu enkephalin
Dynorphin A
1 13
Opioid peptides
Diabetes
